a disorder where there are noncancerous lumps or growths within the ear Canal or on the pinna of the ear (external ear). most lumps are sebaceous cysts but some are bony overgrowths known as exostoses (or osteomas). If large enough they may interfere with hearing. in this case surgical removal may be required.
MHE / mo / HME is a genetic bone disorder in which benign cartilage-capped bone tumors that grow outward from the metaphyses of long bones, growth plates of long bones or from the surface of flat bones throughout the body.
These exostoses / Osteochondroma's can cause numerous problems, including: compression of peripheral nerves or blood vessels; irritation of tendons and muscles resulting in pain and loss of motion; skeletal deformity; short stature; limb length discrepancy; chronic pain and fatigue; mobility issues; early onset arthritis; and an increased risk of developing chondro- sarcoma, reported risk of 2%-5% over life time.
It is not uncommon for MHE / mo / HME patients to undergo numerous surgical procedures throughout their lives to remove painful or deforming exostoses / Osteochondroma's and or to correct limb length discrepancies and improve range of motion.
surgery, physical therapy and pain management are currently the only options available to MHE / mo / HME patients, but their success varies from patient to patient and many struggle with pain, fatigue and mobility problems throughout their lives.
Most individuals with MHE / mo / HME have a parent who also has the condition, however, approximately 10% -20% of individuals with MHE / mo / HME have the condition as a result of a spontaneous Mutation are thus the first person in their family to be affected.