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Exon

Definition

noun, plural: exons

(molecular biology)

1. The protein-coding region in the DNA.

2. The nucleic acid sequence in the DNA, or RNA transcript following genetic splicing.


Supplement

Genes contain exons which are regions coding for proteins and which are interrupted by the unused sequences called introns. Exons have been found to include both sequences coding for amino acids and untranslated sequences. The introns are removed and the exons are joined together to form the final functional mRNA.


Related forms: exonic (adjective).
Compare: intron.
See also: DNA, RNA, translation, mRNA, protein synthesis.


User Contributions / Comments:

  • The base sequences that appear in eukaryotic DNA and are used to make mRNA for a specific protein are the exons of a gene.

(~Dlee7283)


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Results from our forum


exon intron junction

Hi people! Please help me. Do you guys know other software that can predict exon-intron junction apart from GENESCAN, NetGene, FGENESH and RNASPL? I also had tried multiple sequence alignment but I need other software to strengthen my result. Unfortunately the ...

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by elynn
Tue Sep 09, 2014 6:48 am
 
Forum: Molecular Biology
Topic: exon intron junction
Replies: 0
Views: 45

Re: An interesting PCR smearing...I dont know what to do :(

hello all , Even i have a similar problem. I am using 3 different primers to amplify 3 different exons of a gene . 1 of the exon is amplifying very well ( a single bright band ) but the other two exon amplification is not coming properly.and this has occured recently. ( ...

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by priyah
Sat Jun 28, 2014 5:20 pm
 
Forum: Molecular Biology
Topic: An interesting PCR smearing...I dont know what to do :(
Replies: 9
Views: 6523

Gene knockdowns in the wasp Nasonia vitripennis

... genes. To overcome this limitation, we designed an Nv eve morpholino overlapping the translation start site, as well as one directed at the exon-intron junction in the homeobox. These two independent morpholinos are expected to disrupt Nv eve activity and indeed result in comparable phenotypes." ...

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by jonmoulton
Fri Mar 07, 2014 5:57 pm
 
Forum: Molecular Biology
Topic: Gene knockdowns in the wasp Nasonia vitripennis
Replies: 0
Views: 1073

Re: qPCR vs Northern Blot

... first - in Northern blot I had silencing, in qPCR i didn't. As far as your question is concerned - my NB probe covers whole length of mRNA - all exons (it's a short one ~2 kbp total). In case of my PCR primers - FORWARD primer binds in one exon in the middle of mRNA, and REVERSE binds at exon-exon ...

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by Nevthonien
Tue Nov 12, 2013 2:47 pm
 
Forum: Molecular Biology
Topic: qPCR vs Northern Blot
Replies: 4
Views: 2578

Review of exon skipping for human therapeutics

Mullard A. Make or break for first splice-modulating agents. Nat Rev Drug Discov. 2013 Oct 31;12(11):813-5. doi: 10.1038/nrd4151. No abstract available. http://www.nature.com/nrd/journal/v12/n11/full/nrd4151.html This is an interest of mine, as my wife was involved in development of ...

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by jonmoulton
Mon Nov 04, 2013 8:51 pm
 
Forum: Molecular Biology
Topic: Review of exon skipping for human therapeutics
Replies: 0
Views: 870
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