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Dictionary » E » Exon

Exon

Definition

noun, plural: exons

(molecular biology)

1. The protein-coding region in the DNA.

2. The nucleic acid sequence in the DNA, or RNA transcript following genetic splicing.


Supplement

Genes contain exons which are regions coding for proteins and which are interrupted by the unused sequences called introns. Exons have been found to include both sequences coding for amino acids and untranslated sequences. The introns are removed and the exons are joined together to form the final functional mRNA.


Related forms: exonic (adjective).
Compare: intron.
See also: DNA, RNA, translation, mRNA, protein synthesis.

User Contributions / Comments:

  • The base sequences that appear in eukaryotic DNA and are used to make mRNA for a specific protein are the exons of a gene.

(~Dlee7283)


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re: no repeat sequences in exons of genes?

... the gene of interest.....remember its very unlikely to hit a piece of protein coding DNA, due to the fact that introns are way way way bigger than exons - 10-100x bigger at least in most cases i estimate. In fact there are pseudogenes in the human genome which are very strong evidence of this type ...

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by merv
Mon Oct 03, 2011 1:37 am
 
Forum: Genetics
Topic: no repeat sequences in exons of genes?
Replies: 5
Views: 330

Re:

... this can be done from a cDNA clone quite accurately (not completely so), it is one of the most difficult problems in biology to predict what the exons used are without the cDNA sequence. In fact, this is one of the most powerful arguments to say there are an infinite number of genes, not 30,000, ...

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by merv
Mon Oct 03, 2011 12:06 am
 
Forum: Genetics
Topic: can protein size be predicted given genome info?
Replies: 8
Views: 414

can protein size be predicted given genome info?

... with a total genome size of 3 x 10 exp 6 base pairs. In this prokaryote, about 90% of the genome is actually protein-encoding (equivalent to our exons). Assume human to encode 30,000 proteins from a genome of a genome of 3 x 10 exp 9 base pairs. In human, about 1.5% of the genome is exon. From ...

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by vulpes
Tue Sep 06, 2011 2:21 am
 
Forum: Genetics
Topic: can protein size be predicted given genome info?
Replies: 8
Views: 414

no repeat sequences in exons of genes?

... insert a mRNA back into DNA and cause diseases but nowhere in my book did it mention what would happen if a repeat sequence would be put into an exon. My theory would be that if inserted into the exon the repeat sequence would cause a frameshift mutation and cause problems with the splicing and ...

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by vulpes
Sun Sep 04, 2011 3:29 pm
 
Forum: Genetics
Topic: no repeat sequences in exons of genes?
Replies: 5
Views: 330

HELP!!!!!! PCR

If i want to carry out a PCR for gene TP53 and i have selected my exon but exon is small and my designed primer is outside (flanking) the exon (i.e.introns) woukd my primer locations be both side of the mutation can any one explain me my qustion and also ...

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by reshma1212
Thu Jun 09, 2011 6:41 pm
 
Forum: Molecular Biology
Topic: HELP!!!!!! PCR
Replies: 8
Views: 637
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