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Erythroblastosis fetalis

Definition

noun

A medical condition in the fetus or newborn in which many erythroblasts are released in fetal blood from the bone marrow in order to compensate for the red blood cells destroyed by hemolysis that results from maternal-fetal blood group incompatibility, specifically involving the rh factor or the ABO blood groups.


Supplement

For instance, the mother is rH- while the fetus is rH+. When the antibodies of the rH- mother enter fetal circulation the antibodies attack the red blood cells of the rH+ fetus, resulting to hemolysis and anemia in fetus. Symptoms include jaundice, anemia, enlarged liver and spleen. When the condition is moderate or severe, many erythroblasts are present in fetal blood, hence, the name, erythroblastosis fetalis.


Variant: erythroblastosis foetalis

Synonyms:


See also: Rhesus disease, ABO hemolytic disease of the newborn


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foetus induce antibody production in mother?

Do you mean erythroblastosis fetalis here?

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by mcar
Fri Dec 19, 2008 8:02 am
 
Forum: Human Biology
Topic: foetus induce antibody production in mother?
Replies: 3
Views: 2225

Re: erythroblastosis fetalis

The antibody response is to the rh markers. If you are rh-negative, those markers are "foreign," so once exposed you produce antibodies to them. If you are rh-positive, exposure to rh-negative blood doesn't give you something to make antibodies to. I have to disagree about blood mixing, th...

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by Darby
Sat Mar 08, 2008 1:48 am
 
Forum: Human Biology
Topic: erythroblastosis fetalis
Replies: 75
Views: 34752

Re: erythroblastosis fetalis

The mother CAN NOT be Rh + and the baby Rh -, simply because the Rh neg allel is recessive! :P

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by ainda
Wed Mar 05, 2008 5:09 pm
 
Forum: Human Biology
Topic: erythroblastosis fetalis
Replies: 75
Views: 34752

please help me....

Or erythroblastosis fetalis :)

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by Poison
Thu Mar 22, 2007 8:34 pm
 
Forum: Genetics
Topic: please help me....
Replies: 3
Views: 2079

erythroblastosis fetalis

I'll change it back then. lol. Who coined the term "Erythroblastosis Fetalis"? ...As recently as 1946, erythroblastosis fetalis, or hemolytic disease of the newborn, ...

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by Dr.Stein
Tue Jul 26, 2005 11:50 am
 
Forum: Human Biology
Topic: erythroblastosis fetalis
Replies: 75
Views: 34752
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