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Epitope

Epitope

(Science: immunology) That part of an antigenic molecule to which the t-cell receptor responds, a site on a large molecule against which an antibody will be produced and to which it will bind.

See: agretope.


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Creation of virus?

... talking about detection in enviroment or in human after infection/death? I cannot imagine, why it couldn't be designed that way. If you know the epitope, you can simply delete/alter it in such way, it will be recognized by different antibodies

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by JackBean
Sun Mar 27, 2011 11:31 am
 
Forum: Microbiology
Topic: Creation of virus?
Replies: 10
Views: 2994

simple epitope

I learned that there is a lower limit to the size of any potential epitope - is that what this is about-?

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by Darby
Tue Jan 18, 2011 8:50 pm
 
Forum: General Discussion
Topic: simple epitope
Replies: 5
Views: 1497

Re: simple epitope

... for your reply. this is not what the thing is about. I need something like a positive control - a known antibody known to bind a very simple epitope (best would be a loop - hence a nonlinear peptide or protein-fragment) which can be used in in-vitro experiments. Cheers, Chris

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by derChronostat
Tue Jan 18, 2011 11:16 am
 
Forum: General Discussion
Topic: simple epitope
Replies: 5
Views: 1497

simple epitope

you should be able to to raise antibodies only against your epitope (understand - use only that epitope for imunization), or raise polyclonal antibodies and lok, which one will best bind your epitope

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by JackBean
Tue Jan 18, 2011 11:06 am
 
Forum: General Discussion
Topic: simple epitope
Replies: 5
Views: 1497

simple epitope

Hi, I couldn“t rally figure out where to post this question. Does anybody know an antibody that recognizes a very simple epitope - like a single loop? For example a peptide-antibody or an antibody binding to a single "site" on a protein. Most of the antibodies recognize a ...

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by derChronostat
Tue Jan 18, 2011 9:48 am
 
Forum: General Discussion
Topic: simple epitope
Replies: 5
Views: 1497
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