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Epistasis

Epistasis is the interaction between the genes at two or more loci, so that the phenotype differs from what would be expected if the loci were expressed independently. The gene whose phenotype is expressed is said to be epistatic, while the phenotype altered or suppressed is said to be hypostatic.Epistasis is the process of a gene being masked by a mutatey thingyyyyyyyyyyyyyyyyyyyyyyyy.


Example of Epistasis Although the gene for male-pattern baldness is not located on the X chromosome, the sex of the individual determines whether the allele for baldness is dominant or recessive. In males the baldness allele is dominant while in females the baldness allele is recessive. Here, the baldness allele will be represented by B' while the non-baldness alleles will be represented by B.

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Re: Determining if one gene or two seperates phenotypes

... Results will be different if products of genes are on the same biochemical pathway than if they’re on different pathway. For example in epistasis one defective enzyme1(earlier on pathway) masks other functional enzyme2..because they both need to be functional so that you can detect some ...

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by zami'87.
Fri Oct 23, 2009 1:48 pm
 
Forum: Genetics
Topic: Determining if one gene or two seperates phenotypes
Replies: 1
Views: 135

Re: Epistasis Problem

Never mind I ended up answering my own answer lol. There were ten possible combinations that would yield a double recessive.

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by gator
Wed Sep 16, 2009 11:09 pm
 
Forum: Genetics
Topic: Epistasis Problem
Replies: 1
Views: 276

Epistasis Problem

Here is the original problem: Consider the example of epistasis in the coat color of Laborador Retrievers. Recall that the double recessive homozygote animals are yellow with liver noses and eyes, instead of yellow with black noses and eyes; many breeders ...

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by gator
Wed Sep 16, 2009 6:26 pm
 
Forum: Genetics
Topic: Epistasis Problem
Replies: 1
Views: 276

Re: Really puzzled with gene expresseion!!!!

... type AB, you will have both carbohydrates represented on the blood cells. That also goes for multiple alleles. If this didn't help try searching Epistasis, Pleiotropy or something

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by star4ysh
Sun Apr 26, 2009 7:12 pm
 
Forum: Genetics
Topic: Really puzzled with gene expresseion!!!!
Replies: 4
Views: 885

Re: Interesting Human genetic disorder

... ciliopathy. Badano JL, Leitch CC, Ansley SJ, May-Simera H, Lawson S, Lewis RA, Beales PL, Dietz HC, Fisher S, Katsanis N. Dissection of epistasis in oligogenic Bardet-Biedl syndrome. Nature. 2006 Jan 19;439(7074):326-30. Epub 2005 Dec 4 Another intriguing syndrome is Hutchinson-Gilford ...

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by jonmoulton
Wed Apr 08, 2009 3:36 pm
 
Forum: Molecular Biology
Topic: Interesting Human genetic disorder
Replies: 2
Views: 728
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