Dictionary » E » Epinephrine



(Science: drug) a cardiac drug used for cardiac arrest from ventricular fibrillation, ventricular tachycardia, asystole, or pulseless electrical activity; extreme hypotension; bradycardia and heart block.

pharmacologic action: 1. Beneficial mainly due to alpha stimulation - increases systemic vascular resistance and improves coronary and cerebral blood flow. 2. Value of beta stimulation is controversial - increases myocardial electrical activity and strength of contraction, but also increases myocardial oxygen requirements and automaticity.

Dose: cardiac arrest: Recommended: 1 mg iv push every 3-5 min Intermediate: 2-5 mg iv push every 3-5 min Escalating: 1 mg, 3 mg, 5 mg iv push 3 min apart High: 0.1 mg/kg iv push every 3-5 min.

continuous infusion for bradycardia and severe hypotension: 2 - 10 mcg/min.

epinephrine can be delivered via the endotracheal tube. Increase dose 2-2.5 times iv dose.

potential complications: hypertension and tachycardia, arrhythmias, especially ventricular ectopy, myocardial ischemia.

Synonym: adrenaline. a catecholamine secreted by the adrenal medulla in response to stress (trade name Adrenalin); stimulates autonomic nerve action.

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Re: Industrial Society Destroys Mind and Environment

... minutes. The motion goes under awareness to the Limbic system where the Amygdala responds to a perceived threat keying the adrenals to release epinephrine ready for 'fight or flight'. Then 'relaxed' watching TV, the Epinephrine stops, switching to cortisol. The cortisol harms the heart, the ...

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by wript
Mon Feb 03, 2014 12:51 am
Forum: Ecology
Topic: Industrial Society Destroys Mind and Environment
Replies: 45
Views: 47786

The Heart

... slows down the RATE of APs - so how many times it's switched on in a given period of time. Otherwise all correct, and just the reverse for epinephrine. 1. Stroke volume in the amount of blood pumped from a single ventricle and so is entirely dependent on the size of the ventricle and nothing ...

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by Babybel56
Sat Apr 23, 2011 8:26 pm
Forum: Human Biology
Topic: The Heart
Replies: 6
Views: 9885

Re: The Heart

... by sending signals so any change in AP effects muscles? - ACH slows down actional potential, which slows down contractions, which lowers HR? - Epinephrine increases AP signals which increase in heart rate?

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by BioJunior
Sat Apr 23, 2011 7:26 pm
Forum: Human Biology
Topic: The Heart
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cardiac system

... potential of the SA node and thus reduce heart rate. Under conditions of physical or emotional activity sympathetic nerve fibers release norepinephrine, which acts to speed up the pacemaker potential of the SA node thus increasing heart rate. Sympathetic nervous system activity also causes ...

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by BioJunior
Sat Apr 23, 2011 9:18 am
Forum: Human Biology
Topic: cardiac system
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Hormones activating target cells

one could imagine e.g. insulin and epinephrine working at a time ;)

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by JackBean
Mon Jul 19, 2010 5:10 pm
Forum: Cell Biology
Topic: Hormones activating target cells
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