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Endocytosis

Definition

noun

A process in which cell takes in materials from the outside by engulfing and fusing them with its plasma membrane.


Supplement

Most of the extracellular materials that the cells absorb are large polar molecules (e.g. proteins and hormones) that cannot pass through the hydrophobic plasma membrane by simple diffusion.

There are two types of endocytosis, called phagocytosis, which literally means cell-eating, and pinocytosis, which literally means cell-drinking.

Word origin: endo: G., comb. form of éndon: within + cyte: G. kutos, hollow vessel + -osis: expressing state or condition.
Related forms: endocytotic (adjective), endocytic (adjective).
Related phrases: trans-endocytosis.
Compare: exocytosis.
See also: plasma membrane.


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cellular mechanisms that result in symptoms of cholera

... while the A2 chain fits into the central pore of the B subunit ring. Upon binding, the complex is taken into the cell via receptor-mediated endocytosis. Once inside the cell, the disulfide bond is reduced, and the A1 subunit is freed to bind with a human partner protein called ADP-ribosylation ...

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by adithya528
Tue Dec 11, 2012 1:49 pm
 
Forum: Cell Biology
Topic: cellular mechanisms that result in symptoms of cholera
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Views: 1063

caveolae and caveolin1

... types, especially in endothelial cells and adipocytes. have several functions in signal transduction.[1] They are also believed to play a role in endocytosis, oncogenesis, and the uptake of pathogenic bacteria and certain viruses. 2. Caveolins are a family of integral membrane proteins. involved ...

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by taruntbiotech
Mon May 14, 2012 5:10 pm
 
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Topic: caveolae and caveolin1
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Protein expression but no mRNA

... The leukemia I work on is characterized by a SLOW progression only partly due to proliferation and even more due to inhibited apoptosis. Is endocytosis a completely unthinkable (and maybe stupid) suggestion?

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by evamik
Wed Feb 22, 2012 2:01 pm
 
Forum: Molecular Biology
Topic: Protein expression but no mRNA
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looking for dyes that won't stain cells

Hi all, I'm looking for a recommendation: I need a cheap fluorescent dye that won't stain any part of my NIH-3T3 cells(a little endocytosis is OK) but is also soluble in water. So basically, rhodamine/fluorescein won't work because they do tend to get through the membrane of unhealthy ...

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by tigerrat
Tue Jan 10, 2012 2:14 am
 
Forum: Cell Biology
Topic: looking for dyes that won't stain cells
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Molecular Cell Biology

Can anyone help me with the answers to (b) and (c)?? I'm completely stuck :( Problem 2 - Endocytosis of EGF and a fluid phase-marker (HRP) (70 marks) Cells take up extracellular molecules by receptor-mediated endocytosis (RME) and by fluid phase endocytosis (FPE). The ...

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by Freckles
Wed Dec 07, 2011 11:24 pm
 
Forum: Cell Biology
Topic: Molecular Cell Biology
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