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Effect modifier

Effect modifier

a factor that modifies the effect of a putative causal factor under study; e.g., age is an effect modifier for many conditions.

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Genetics behind hazel eyes?

... the genetics behing hazel eyes, saying that there is a new undiscovered modifier gene 'M' which produced more melanin for the 'G' (green eye gene) ... brown, but darker than green. There is also an 'm' gene which does no effect. It then states the list of genetic combinations which in theory would ...

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by Montario
Fri Aug 03, 2012 10:00 pm
Forum: Genetics
Topic: Genetics behind hazel eyes?
Replies: 1
Views: 11662

Re: What is Second-Order Selection?

... let us assume that alleles at this locus do not differ in their direct effect on the fitness of their bearers - they do not directly affect survival ... via mutations they allow or prevent. Such a locus is often called a MODIFIER of mutation, and the action of natural selection on such a locus ...

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by Luxorien
Sat Mar 03, 2012 8:12 pm
Forum: Evolution
Topic: What is Second-Order Selection?
Replies: 1
Views: 2633

Re: splicing MO vs translation MO

... be an off-target interaction but instead is the p53-mediated apoptotic effect. If this is the case, the effect is caused not by the Morpholino directly ... p53 apoptotic effect, you should see the same phenotype from the splice modifier and the translation blockers since the p53 effect is triggered ...

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by jonmoulton
Tue Aug 19, 2008 4:22 pm
Forum: Molecular Biology
Topic: splicing MO vs translation MO
Replies: 14
Views: 12693

The Fiber Disease

... AND THE STICTION PROBLEM IN MEMS" Interest in the Casimir Effect has increased in recent years with the improvement in micro and nano-technology. ... and deconjugation of members of the family of the small ubiquitin-like modifier SUMO. SUMO-modification of proteins is important in many biological ...

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by Nadas Moksha
Fri Aug 25, 2006 3:09 am
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6245062

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