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Dose

Dose

1. (Science: pharmacology) a quantity to be administered at one time, such as a specified amount of medication.

2. (Science: radiobiology) a general term denoting the quantity of radiation or energy absorbed. For special purposes it must be appropriately qualified. If unqualified, it refers to absorbed dose. Unit of absorbed dose is the rad. The si unit is the gray (1 gy = 1 j kg-1 = 100 R).

Origin: gr. Dosis = a giving a measured portion of medicine taken at any one time.The quantity of an active agent (substance or radiation) taken in or absorbed at any one time.Treat with an agent; add (an agent) to; The ray dosed the paint.Pertaining to the amount of a particular substance within an organism, either naturally or implanted.


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"dose"-response curves

I have always wondered why dose-response curves are constructed against the concentration of a drug rather than the amount of a drug. Typically, an effect increases or decreases with increasing concentration in g/l or mol/l. Why not graphing ...

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by Mathias
Wed Feb 25, 2015 3:23 pm
 
Forum: Cell Biology
Topic: "dose"-response curves
Replies: 0
Views: 280

Re: Human Collembola Infestations

... didn't bother to check my skin and just went on to prescribe ivermectin. By then I was going quiet nuts and took a slightly higher than necessary dose of ivermectin. The next day I thought I was dying along with the bugs inside of me. I had to FORCE myself to breathe, my central nervous system ...

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by sammygirl
Thu Feb 05, 2015 2:16 pm
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 132478

Human Collembola Infestations

... used by ~6 million people world-wide and no known dangerous side effects. I didn't have ANY. Just relief. Make sure not to delay the follow-up dose too long; otherwise the arthropod will have time to mature and reproduce more eggs. Then the whole cycle starts over.

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by urthchik
Mon Oct 06, 2014 6:38 pm
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 132478

Human Collembola Infestations

... should NOT be done for parasitic infections because it lowers immunity and allows them to propagate uninhibited. I finally took ivermectin in 2 doses. The first dose slowed it down but the itching returned within a few days. My guess is that the next hatching of eggs occurred and they are impervious ...

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by urthchik
Sun Oct 05, 2014 12:20 am
 
Forum: Human Biology
Topic: Human Collembola Infestations
Replies: 47
Views: 132478

Re: Any ideas for vaccine development or anti-viral drugs???

... P-PMO designed to base pair with the translation start site region of EBOV VP35 positive-sense RNA generated sequence-specific and time- and dose-dependent inhibition of EBOV amplification in cell culture. The same oligomer provided complete protection to mice when administered before or ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12594
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