Dictionary » D » Dolichol



(Science: chemical) Terpenoids with 13-24 isoprene units and a terminal phosphorylated hydroxyl group. Function as transmembrane carriers for glycosyl units in the biosynthesis of glycoproteins and glycolipids.

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protein modification and trafficking

... carbohydrates take place and even the protein folding is done in ER by enzyme such as protein disulfide isomerase and carbohydrates are added by dolichol carrier. Is trafficking is done by means of trans & cis golgi complex by means of vesicles which carry the proteins to the targeted sites ...

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by knsprasad
Sun May 25, 2008 10:58 am
Forum: Molecular Biology
Topic: protein modification and trafficking
Replies: 1
Views: 1816

mannose extraction with methanol/chloroform

yes,i think you have it exactly on target. Glycoprotein synthesis occurs by attaching sugars evolved from dolichol phosphate. Dolichol, of course, is a lipid, and can be extracted by using methanol/chloroform.

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by MrMistery
Thu Apr 24, 2008 10:22 am
Forum: Cell Biology
Topic: mannose extraction with methanol/chloroform
Replies: 2
Views: 2430

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