covalent adducts between chemical mutagens and dna. Such couplings activate dna repair processes and, unless repaired prior to dna replication, may lead to nucleotide substitutions, deletions, and chromosome rearrangements. (rieger et al., glossary of genetics: classical and molecular, 5th ed)
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... theory is that the radical flavonoid (like quercetin) molecule forms a DNA adduct, like mutagenic substances form a DNA adduct and causes DNA to ... bind to DNA, which makes it able for the radical flavonoid to form adducts on DNA. Then, if the DNA adduct isn't removed before cell division ...
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