Dictionary » D » Digoxin

Digoxin

Digoxin

(Science: chemical) a cardiotonic glycoside obtained mainly from digitalis lanata; it consists of three sugars and the aglycone digoxigenin. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small.

Pharmacological action: anti-arrhythmia agents, cardiotonic agent, enzyme inhibitors.

chemical name: Card-20(22)-enolide, 3-((O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy)-12,14-dihydroxy-, (3beta,5beta,12beta)-


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Na/K ATP-ase Reversal

... vasodilators (venous dilation, reduce preload), calcium receptor antagonists (e.g. verapamil reduced afterload)...etc. but cardiac glycosides like digoxin increase heart workload... doesn't this make angina worse in the long run?... and what about the risks of cardiac arrhymias with the drugs... ...

See entire post
by Revenged
Sat Feb 24, 2007 10:47 pm
 
Forum: Cell Biology
Topic: Na/K ATP-ase Reversal
Replies: 5
Views: 4671

The Fiber Disease

... molecule is selected from the group consisting of acetaminophen, amilacin, amitriptyline, chloramphenical, cyclosporine, desipramine, digitoxin, digoxin, disopyramide, ethosuximide, flecainide, gentamicin, imipramine, hanamycin, lidocaine, methotrexate, carbamazepine, N-acetylprocainamide, metilmicin, ...

See entire post
by London
Wed Dec 20, 2006 8:43 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5482935

The Fiber Disease

... gate is controlled by a molecule that, like some spiteful doorman, closes the passage when it runs into a particular target molecule. To detect digoxin, a heart medication, Cornell attached to the gates compounds that bind to the drug. When it is present, the gates swing shut, electrical flow ...

See entire post
by Maggie Mae
Sat Dec 09, 2006 4:26 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5482935


This page was last modified 21:16, 3 October 2005. This page has been accessed 1,953 times. 
What links here | Related changes | Permanent link