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Differentiation antigen

Differentiation antigen

Any large structural macromolecule that can be detected by immune reagents and that also is associated with the differentiation of a particular cell type or types. Many cells can be identified by their possession of a unique set of differentiation antigens. There should be no implication that the antigens cause differentiation.


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Re: Cytokine - Receptor concepts

... of adaptive immune response. But this response is triggered by specific antigen recognition by T lymphocites. Otherwise, T lymphocites can be usefull ... Provide amplification mechanisms by augmenting B cell proliferation and differentiation (2) They determine the types of antibodies produces by ...

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by marla
Tue Jun 01, 2010 9:08 pm
 
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 14861

Re: T-cell activation

... head to secondary lymphod tissues in hope of finding their specific antigen there, presented by APCs. I assume here the differentiation means they become activated T cells (as opposed to naive T cells) and gain ...

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by biohazard
Mon Feb 08, 2010 7:03 am
 
Forum: Molecular Biology
Topic: T-cell activation
Replies: 2
Views: 2282

DIFFERENTIATION

Hi, I am looking for some basic information about differentiation in general. Do cells actively divide during the differentiation process? I mean, when a progenitor cell is activated (by antigen or some other stimuli), do they keep dividing during the various stages of ...

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by epicionado
Fri May 08, 2009 6:10 am
 
Forum: Cell Biology
Topic: DIFFERENTIATION
Replies: 1
Views: 2920

Re: T cell differentiation

Hi, I am looking for some basic information about differentiation in general. And T-cell differentiation is a great system. Since ... the differentiation process? I mean, when a progenitor cell is activated (by antigen or some other stimuli), do they keep dividing during the various stages ...

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by epicionado
Fri May 08, 2009 6:08 am
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 16
Views: 33328

Re: T cell differentiation

... for the explanation biohazard. I think i've got it now: The T cells are produced in the thymus as naive CD4+ and CD8+ cells and then recognise the antigen in the lymph nodes (mainly) but recently there have been RTE's discovered which are not yet CD4 or CD8 positive and differentiate upon activation

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by Immunologyordie
Thu Apr 16, 2009 6:41 pm
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 16
Views: 33328
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