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Dideoxynucleosides

Dideoxynucleosides

(Science: chemical) Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.

Pharmacological action: antimetabolites, antiviral agents, reverse transcriptase inhibitors.


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... d dna's doble helix......... nucleosides......u hv fr eg- adenosine,guanosine....n ol.....dey r basically sugars attchd to bases........ dunno abt dideoxynucleosides.......bt deoxynucleosides r nthng bt sugar structrs werin d hydroxyl grp is replcd by H. ....... n dunno abt dNTP n AMP.........!

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by meenkashi
Wed Sep 03, 2008 5:44 pm
 
Forum: General Discussion
Topic: Terminology
Replies: 2
Views: 509


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