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Dicentric

Pertaining to a chromosome that possesses two [[centromeres.


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Karyotyping and Probing

i would try a FISH experiment. Since a Robertsonian translocation is a dicentric fusion and the acentric parts fragment will be lost, you should be able to detect a Robertsonian translocation using probes for ed 14 & 21 (you'll find only 1 strand of both ...

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by sdekivit
Fri Jul 13, 2007 8:02 am
 
Forum: Genetics
Topic: Karyotyping and Probing
Replies: 1
Views: 1404

The Fiber Disease

... the ELF and RF range led to significant increases in chromosomal abnormalities in human fibroblasts (skin cells), such as gaps, breaks, rings, dicentric (two centromeres) chromosomes and fragments. Gaps increased 4-fold, breaks 2-fold, and dicentric chromosomes and acentric fragments 10-fold. ...

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by Nadas Moksha
Wed Sep 06, 2006 2:58 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5480331

centromere

in a robertsonian translocation actually a dicentric chromosome is created, but they act as one centromere.

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by sdekivit
Thu Mar 30, 2006 5:46 pm
 
Forum: Cell Biology
Topic: centromere
Replies: 8
Views: 4098


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