Dhfr

... ovary, a commercial cell line for producing pharmaceutical proteins By the way, I have a question: There are many kind of CHO (eg. CHO K1, CHo dhfr-) available commercially, but they all lack of biosynthetic pathway of proline. Why isn't CHO which can grow in medium no proline used ?

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I'm doing with CHO K1 and CHO dhfr-, but I don't have much information about them. I want to know their origin, biochemistry and physiology. If someone know webs or aticles, etc...about them, would you mind sharing with me ? Thank you very ...

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