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Depolarisation

Depolarisation

The process or act of neutralising polarity, depriving of polarity, or the result of such action; reduction to an unpolarised condition.

(Science: physiology) The reversal of the resting potential in excitable cell membranes when stimulated i.e., the tendency of the cell membrane potential to become positive with respect to the potential outside the cell. A positive shift in a cells resting potential (that is normally negative), thus making it numerically smaller and less polarized, for example 90mV to 50mV.

(Science: optics) depolarisation of light, a change in the plane of polarization of rays, especially by a crystalline medium, such that the light which had been extinguished by the analyser reappears as if the polarization had been anulled. The word is inappropriate, as the ray does not return to the unpolarised condition.

Origin: cf. F. Depolarisation.


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Re: On Calcium mediated exocytosis and the synaptotogmin fam

... is part of a protein kinase right? i'm not sure if i'm answering the question your asking but i just thought i'd point out that the initial depolarisation responsible for calcium mediated exocytosis can occur in diffferent ways... 1) Opening of sodium channels - e.g. which as you said occurs ...

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by Revenged
Mon Jul 09, 2007 10:40 am
 
Forum: Cell Biology
Topic: On Calcium mediated exocytosis and the synaptotogmin family
Replies: 3
Views: 823

I need an answer please

... and what you are talking about is fasciculations... but you must remember that excessive stimulation of nicotinic acetylcholine receptors causes depolarisation block... this is how muscle relaxants like suxamethonium cause paralysis...

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by Revenged
Sat Mar 24, 2007 5:47 pm
 
Forum: Physiology
Topic: I need an answer please
Replies: 8
Views: 2600

Bio+ check + please!

c cell membrane becoming more permeable to Na+ is due to depolarisation of the neurone, which is a passive process...

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by Revenged
Sat Feb 24, 2007 10:34 pm
 
Forum: General Discussion
Topic: Bio+ check + please!
Replies: 1
Views: 405

Electric shocks, anybody??

the heart depends on cells to transmit their potential from one to another. If the pacemaker cells get damaged(could happen if depolarisation is induced in the refractary period) the impulse won't get from the sinoatrial node to the rest of the heart. The heart simply stops. Just a hypothesis...

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by MrMistery
Fri Feb 02, 2007 6:14 pm
 
Forum: Human Biology
Topic: Electric shocks, anybody??
Replies: 10
Views: 1381

Evolution of inhibitory synapses in rods

... system in the first place? What's the evolutionary reason for it that makes it better to do this than it is to have a simple 'light --> depolarisation' system that is the intuitive way of doing things? Any ideas??

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by robmcm
Thu Mar 30, 2006 1:33 pm
 
Forum: Evolution
Topic: Evolution of inhibitory synapses in rods
Replies: 1
Views: 916
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