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Depletion

as a biology term:

1. The act or process of emptying, removal of a fluid, as the blood.

2. Exhausted state which results from excessive loss of blood.

Origin: L. Deplere = to empty

general definition of depletion:

To deplete*

*(deplete: to remove, take away from, create an absence of, etc.)

Example: the PGFOSC will deplete you.