It is an antimetabolite, especially when it is converted to deoxyuridine triphosphate and incorporated to DNA during replication. The presence of side groups bound to the uracil component prevents base pairing, hence, interferes with DNA synthesis.
Related term: Deoxyuridine 1-hydroxylase.
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... codes: M=A+C_________D=A+G+T R=A+G_________B=C+G+T W=A+T________N=A+G+C+T S=C+G_________I=deoxyinosine (will pair with all 4) Y= C+T________U=deoxyuridine (will replace T like in RNA) K=G+T V=A+C+G H=A+C+T
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