Dictionary » D » Denatured

Denatured

Definition

adjective

(1) Having been altered in natural quality.

(2) Of, or pertaining to, a molecule (such as a protein or a nucleic acid) wherein its chemical structure is altered through chemical or physical means so that some of its original properties are lost or diminished.

(3) Of, or pertaining to, a food or drink (often an alcohol) that is made unfit for human consumption (in case of alcohol, by the addition of methanol) while its use for other purposes is retained.


Supplement

A protein that is said to be denatured means that its tertiary structure is caused to unfold possibly by heat, alkali, acid, or by other chemical or physical means, making the molecule lose its original state and become biologically inactive.

A denatured nucleic acid such as DNA means that the paired strands have become separated into individual strands.

A denatured alcohol (ethanol) does not mean its structure is changed. It only means that its feature as a beverage has been removed by adding toxic and bitter tasting chemicals. That is why it is still useful for other purposes, such as a solvent.


Word origin: Latin -, (away from, of, out of) + nature(d).

Related term: denaturation


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Results from our forum


PCR & Agarose gel electrophoresis

... the same as theirs? What about the voltage across the gel and the time of the run? Did you expose the RNA to light too much? It's possible you denatured them. Also, there may have been RNAses in your extract that could have reduced copy count drastically.

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by jyaron
Sat Sep 05, 2009 10:32 pm
 
Forum: Molecular Biology
Topic: PCR & Agarose gel electrophoresis
Replies: 3
Views: 119

Re: Stomach bloating and weight gain

Not so. Not most ingested enzymes will be denatured and destroyed upon entering the stomache. Stomach acids do not secrete until the food is ingested and takes a couple of minutes to "gear up" for the meal coming (acinar cells and pancreatic ...

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by MichaelXY
Mon Jul 13, 2009 8:08 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 299
Views: 483258

Stomach bloating and weight gain

Not so. Not most ingested enzymes will be denatured and destroyed upon entering the stomache. Stomach acids do not secrete until the food is ingested and takes a couple of minutes to "gear up" for the meal coming (acinar cells and pancreatic ...

See entire post
by kolean
Fri Jul 10, 2009 3:49 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 299
Views: 483258

Re: Stomach bloating and weight gain

... meal that will undoubtly have soy or corn in it. You seem to have good background in biology, surely you must know most ingested enzymes will be denatured and destroyed upon entering the stomach. Perhaps if you dilute your system with water and take the enzyme exactly when your eating your food, ...

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by MichaelXY
Thu Jul 09, 2009 9:04 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 299
Views: 483258

Re: Stomach bloating and weight gain

... the pH level of the stomach. This brings me to my second point. The digestive enzymes in the stomach work to break down proteins such as other denatured enzymes, converts them to peptides. At the end of the day, your enzyme suppliment becomes nothing more than a steak. I noticed on the UDO ...

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by MichaelXY
Wed Apr 29, 2009 7:04 am
 
Forum: Physiology
Topic: Stomach bloating and weight gain
Replies: 299
Views: 483258
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