Dictionary » D » Deletion

Deletion

Deletion

(Science: genetics) a chromosome abnormality in which part of a single chromosome has been lost.


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I have got some BIG issues! forgive the long post

... group immunogen, but it is absent from a relatively large segment of the population (i.e. Rh-negative phenotype), mainly as the result of RHD gene deletion. RHCE exists in four allelic forms and each allele determines the expression of two antigens in Ce, ce, cE or CE combination (RHCE is the collective ...

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by saddy51
Sun Jan 04, 2015 10:39 am
 
Forum: Genetics
Topic: I have got some BIG issues! forgive the long post
Replies: 1
Views: 1768

Re: Any ideas for vaccine development or anti-viral drugs???

... to the plasma membrane during budding. Involvement of other vps proteins in EBOV budding has not been established. Therefore, we used VP40 deletion analysis, virus-like particle-release assays, and confocal microscopy to investigate the potential role of ESCRT-1 proteins VPS4, VPS28, and ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 12545

Re: microsatellite instability

OK, another question: I can see how insertion/deletion can be detected by fragment analysis, but incorporation of a wrong nucleotide wouldn't cause change in the length of amplicon, so can that also be detected by fragment analysis?

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by kk
Thu Jul 10, 2014 2:45 pm
 
Forum: Molecular Biology
Topic: microsatellite instability
Replies: 3
Views: 3446

Re: Gene deletion

Thanks for your relpy! Maybe I wasn't clear enought but I want to delete genes in my drug-multiresistants strains without changing the rest of the bacterial strain... The drug resistancy is naturally found in both plasmid and chromosome. Anyway, I am curious to know how does it works with the hetero...

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by clefg
Thu Sep 05, 2013 2:42 pm
 
Forum: Molecular Biology
Topic: Gene deletion
Replies: 5
Views: 3492

Gene deletion

... to almost all antibiotics. Does anyone knows an alternative selection for my mutants (without antibiotics) or an alternative protocol for gene deletion? Thanks for your help!

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by clefg
Wed Sep 04, 2013 3:56 am
 
Forum: Molecular Biology
Topic: Gene deletion
Replies: 5
Views: 3492
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