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Dehydrogenases

Dehydrogenase

(Science: enzyme) enzyme that oxidizes a substrate by transferring hydrogen to an acceptor that is either NAD/NADP or a flavin enzyme.


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ETC - purpose of having different dehydrogenases?

Hey guys, There's something I'm a bit confused by. I've been reading about how E. coli can have different NADH dehydrogenase complexes (more specifically, NDH-1 and NDH-2). One major difference between the two is the fact that NDH-1 is a coupling site (so pumps out protons while transferring electro...

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by keetner
Sat Dec 15, 2012 2:28 am
 
Forum: Molecular Biology
Topic: ETC - purpose of having different dehydrogenases?
Replies: 1
Views: 2342

Reduction of NAD+

You need to understand the difference between substrate and cofactor. The NAD+/NADH is cofactor. The dehydrogenases take hydrogens from substrates and put them to the cofactors, which can be subsequently reoxidized either with the same enzyme (typically flavin coenzymes) ...

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by JackBean
Tue Jun 14, 2011 8:32 am
 
Forum: Molecular Biology
Topic: Reduction of NAD+
Replies: 1
Views: 6783

Reduction of NAD+

... if somebody could do a little explaining. Even if they only know a tiny bit =). Ok, so I know that NAD+ is reduced to NADH by the action of dehydrogenases. Which means means that it gains electrons (2 electrons I think) and a hydrogen. I don't really know what a dehydrogenase is only that ...

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by illuminada
Sun Jun 12, 2011 5:18 am
 
Forum: Molecular Biology
Topic: Reduction of NAD+
Replies: 1
Views: 6783

Question about metabolism and some chemical things?

... often used by GTPases or in Kreb's cycle. NAD and FAD are electron carriers or electron acceptors (depends on point of view), they are used by the dehydrogenases etc.

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by JackBean
Tue Mar 15, 2011 2:11 pm
 
Forum: Molecular Biology
Topic: Question about metabolism and some chemical things?
Replies: 7
Views: 7852

The Fiber Disease

... while MTT (3-[4, 5-dimethylthiazol-2yl]-2, 5-diphenyl tetrazolium bromide) identifies metabolic activity through its reduction by cellular dehydrogenases to microscopically visible deposits of insoluble formazan. MTT-negativity has earlier been shown to correlate with absence of growth ...

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by tamtam
Mon Nov 27, 2006 3:26 pm
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 5505169
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