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Degeneracy

Degeneracy

(Science: molecular biology) The coding of a single amino acid by more than one base triplet (codon).

Of the 64 possible codons, three are used for stop signals, leaving 61 for only 20 amino acids. Since all codons can be assigned to amino acids, it is clear that many amino acids must be coded by several different codons, in some cases as many as six.


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Quick Question-

... retroviral vector in a bicistronic configuration of 2Cα-IRES-2Cβ (kindly provided by Phil Holler and Jianzhu Chen, MIT). The 5 codon amino acid degeneracy library in CDR3α of the 2C TCR (GFASA, positions 99–103) was created by overlap extension PCR. SOE-PCR-overlap regions between two preSOE ...

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by vithuramaharajah
Fri Apr 17, 2009 9:55 pm
 
Forum: Molecular Biology
Topic: Quick Question-
Replies: 1
Views: 467

diffusion and osmosis. help me please?

... The chances of throwing a 555 is the same as throwing a 123. However! The states as defined by the sum of the dices is not equally likely due to degeneracy. For example, there is only one configuration that adds up to 3:if you throw 111. However there's a number of configurations you can throw ...

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by mith
Thu Oct 02, 2008 3:37 am
 
Forum: Cell Biology
Topic: diffusion and osmosis. help me please?
Replies: 1
Views: 2757

synonymous vs conservative missense mutation

hi hiro! synonymous mutations are those that donot change the amino acid even if there is a substitution of one base in the place of other(degeneracy of genetic code) and it doesnt make any change in the protein structure or funtion or watever u say.but non-synonymous mutations change the aminoacid ...

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by ramya
Mon Sep 24, 2007 6:29 am
 
Forum: Genetics
Topic: synonymous vs conservative missense mutation
Replies: 6
Views: 2257

Degenerate Primers

... minutes. For: YGMKGAGGARRACATWASWG Rev: CAARTTWCCAAYSRYMCCMA Those are the two primers I got. Everything except for you ATGC's have an equivalent degeneracy right. I limited my primer search to 256 degeneracy max. What is the maximun degeneracy i should use? Cheers, Chris

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by c1bl
Wed Aug 01, 2007 4:05 pm
 
Forum: Molecular Biology
Topic: Degenerate Primers
Replies: 2
Views: 1078

The Fiber Disease

... nanofibers and this disease. Under the wise guidance of Wall Street and insurance companies, American Medicine has fallen into an amazing state of degeneracy. Medical care is unavailable for many, access is limited for most, and research money is frequently unavailable except from major drug companies. ...

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by Maggie Mae
Wed Dec 20, 2006 4:33 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 748687
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