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Defective viruses

Defective viruses

viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called satellite viruses, are able to replicate only when their genetic defect is complemented by a helper virus.


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Recombination in RNA viruses,Ruzic,Kovac

... Maria – Helena Ružić, Ana Kovačević Aspects of recombination in RNA viruses Introduction RNA viruses deserve their reputation as Nature's swiftest ... 1992). Despite producing distinct kinds of hybrid RNAs, as well as defective interfering (DI) RNAs (Lazzarini et al., 1981), the different types ...

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by anakovacevic
Sat Jun 12, 2010 8:28 pm
 
Forum: Cell Biology
Topic: Recombination in RNA viruses,Ruzic,Kovac
Replies: 2
Views: 36074

Re:

... be inserted into the genome just like the viral DNA would be. Normally, viruses are not specific in their insertion placement, meaning if you tossed ... question. Now, to actually help answer the question; the location of a defective gene in a genome can be completely useless information, or it ...

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by sableg
Thu Dec 10, 2009 1:33 pm
 
Forum: Genetics
Topic: Location of defective gene assisting in future treatments
Replies: 6
Views: 5228

Location of defective gene assisting in future treatments

... be inserted into the genome just like the viral DNA would be. Normally, viruses are not specific in their insertion placement, meaning if you tossed ... question. Now, to actually help answer the question; the location of a defective gene in a genome can be completely useless information, or it ...

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by Eous
Thu Dec 10, 2009 8:38 am
 
Forum: Genetics
Topic: Location of defective gene assisting in future treatments
Replies: 6
Views: 5228

Location of defective gene assisting in future treatments

So the exact question is "How can knowing the location of a defective gene assist in developing future products or treatments for that ... on gene therapy and I'm thinking I should base my answer around using viruses to insert genes into cells that are needed. I understand that this ...

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by sableg
Wed Dec 09, 2009 8:52 pm
 
Forum: Genetics
Topic: Location of defective gene assisting in future treatments
Replies: 6
Views: 5228

Re: Cancer

... that cascade is activated even without proper signal. Sometimes there's defective receptor,G protein or other protein kinases..Sometimes gene is ... is lost because genes for those proteins are defective.In other cases,viruses bear oncogenes and can cause transformation of cell. Point is that ...

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by zami'87.
Sat Dec 05, 2009 5:06 pm
 
Forum: Human Biology
Topic: Cancer
Replies: 10
Views: 4918
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