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De novo pathway


noun, plural: de novo pathways

(biochemistry) A biochemical pathway where a complex biomolecule is synthesized anew from simple precursor molecules.


An example is the synthesis of complex biomolecules from simple units, e.g. of protein from amino acids.

This is in contrast to salvage pathway where simple molecules are being recycled after partial degradation.

Compare: salvage pathway

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The Fiber Disease

... the Li(+) tolerance of E. coli, suggesting that the sulfur-assimilating pathway is a likely target of salt toxicity in bacteria as well." http://www.knockoutscience.com/showabstract.php?pmid=16391050 ... used by eukaryotic cell surface proteins for membrane attachment. De novo synthesized ...

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by Nadas Moksha
Wed Oct 04, 2006 6:28 am
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6245769

de novo and salvage pathways of nucleotides

In nucleotide biosynthesis are pyrimidines synthesized only by de novo pathways and purines synthesized only by salvage pathways or can they both be synthesized by ...

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by virlomi_stone
Thu Mar 23, 2006 7:40 am
Forum: Molecular Biology
Topic: de novo and salvage pathways of nucleotides
Replies: 0
Views: 2231

De novo synthesis

... in the cytopasm. (i guess) ribose is made by utilising the HMP shunt pathway of glucose breakdown nitrogen bases (purines n pyrimidines) have there own de novo synthetic pathways from simpler components.

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by cytochromeP
Fri Apr 15, 2005 12:25 pm
Forum: Cell Biology
Topic: What is the source of new nucleotides for replication?
Replies: 11
Views: 11274

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