Dictionary » D » De novo

De novo

Definition

‘’adverb & adjective

(1) Anew; afresh; beginning again; from the start.

(2) New; not present previously; just beginning.


Supplement

The term ‘’de novo’’ is often italicized when written to indicate that it is a Latin phrase. An example of its usage is:

  • biochemistry : ’’de novo’’ synthesis of a complex molecule, which refers to the biochemical pathway where a complex biomolecule is synthesized anew from simple molecules.
  • bioinformatics : ’’de novo’’ peptide sequencing, a form of sequencing.
  • genetics : ‘’de novo’’ mutation, a genetic mutation that neither parent possessed nor transmitted.


Word origin: From the Latin adverb dē novō (“‘from the new’”); from dē (“‘from’”) + novō, the ablative singular of novus (“‘new’”).

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How to predicate miRNA target in non-model animals

Hi, guys I am trying to predicate miRNA target from a non-model fish species. I have sequenced small RNA and mRNA and then proceed to do the de novo assembly to get the transcriptome. There is no genome sequence available for this fish. Any idea about how to predicate the miRNA target without ...

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by Rocmayflower
Mon Oct 21, 2013 11:45 am
 
Forum: Bioinformatics
Topic: How to predicate miRNA target in non-model animals
Replies: 1
Views: 919

Re: Theories - Origin of Life

... natural selection plays a strong role in the evolution of these genes. Because, as any biologist will tell you, natural selection doesn't work de novo . It takes what is already there and tweaks it. Complex structures don't evolve overnight. You don't need the whole mousetrap at once because the ...

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by Luxorien
Sun Sep 23, 2012 6:57 am
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 560
Views: 888125

Re: Theories - Origin of Life

... visuals of the complexity of genomic interactions. The simple answer to your question is that genes are legos made of legos. Nothing is created de novo ; it's all built modularly. Do a Google search on "gene origins."

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by Luxorien
Wed Sep 19, 2012 3:23 am
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 560
Views: 888125

Explain why Genetic Code is called "Rosetta Stone" of life?

Disagree - mRNA does not produce amino acid, essential ones in humans coming from diet rather than synthesis de novo. It the blueprint for synthesis of proteins that are composed of amino acids. The bricklayer doesn;t make the bricks. In any case, the student did not broaden the ...

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by JorgeLobo
Thu May 31, 2012 11:50 am
 
Forum: Genetics
Topic: Explain why Genetic Code is called "Rosetta Stone" of life?
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Views: 8424

Theories - Origin of Life

... test tube. If I took that many E. coli and let them divide three times (multiplying the population by 8), you would produce the mutation de novo about 7 times. This would take about an hour. The point is that generating any particular mutation is easy . Suppose there is a mutation that has ...

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by AstraSequi
Tue Mar 27, 2012 2:30 am
 
Forum: Evolution
Topic: Theories - Origin of Life
Replies: 560
Views: 888125
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