Dictionary » C » Cytotoxicity

Cytotoxicity

Definition

noun

The state of being cytotoxic or the quality of being toxic to cell.


Supplement

Lymphocyte-mediated cytotoxicity is an example of cytotoxicity in organisms. For instance, T lymphocytes (the cytotoxic type) cause lysis of cells with their synthesis of cytolytic proteins (e.g. perforin).


Word origin: cyto- (cell) + toxicity

Related forms: cytotoxic (adjective)

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What does this mean??? Please help

... Ly antisera we used, diluted 1 :10, were absorbed once with 120 x 10 8 syngeneic thymus + LNC/ml to remove autoantibody . Complement (C)-Dependent Cytotoxicity Assay . 10-40 x 10 8 cells/ml ("Cr-labeled ; 30 min, 100 juCi/ml) were incubated with Ly antiserum diluted in phosphate-buffered saline ...

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by speakers2
Sun Oct 16, 2011 1:06 am
 
Forum: General Discussion
Topic: What does this mean??? Please help
Replies: 0
Views: 2114

Discrepancy of trypan blue and BrdU incorporation

I have assessed the effect of drug on stellate cells using trypan blue and Brdu incorporation method. Since trypan blue is to test the cytotoxicity and BrdU incorporation labelled the proliferate cells,therefore,I assumed the IC50 obtained should be not much difference.To my surprise, there ...

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by GisLove
Fri Mar 25, 2011 9:58 am
 
Forum: Cell Biology
Topic: Discrepancy of trypan blue and BrdU incorporation
Replies: 0
Views: 822

Re: Electrophoresis of ionic complexes

... good idea to try. As you may have guessed, this siRNA-polymer complex is for physiological use, so I'm not sure how paraformaldehyde would effect cytotoxicity, efficacy, and how easily the siRNA would dissociate in the body. Do you happen to suggest any papers that may point me in the right direction?

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by dhkwak
Fri Jan 07, 2011 2:22 am
 
Forum: Molecular Biology
Topic: Electrophoresis of ionic complexes
Replies: 6
Views: 3321

Anti-metastasis and Cytostasis, Differentiation between the

... currently using the C6, rat glioma cells and HeLa, human cervical cancer cells to perform the experiment. I have used MTT assay to determine the cytotoxicity of the compounds on the same cell lines. Can anyone please help me out by giving me an idea of a method to differentiate both of these ...

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by Gemini
Fri Jul 17, 2009 3:40 pm
 
Forum: Cell Biology
Topic: Anti-metastasis and Cytostasis, Differentiation between the
Replies: 0
Views: 1935

What does peroxynitrite do in cytotoxicity of cells?

... zoology professor entitled "DNA strand breakage, activation of poly(ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity in macrophages and smooth muscle cells exposed to peroxynitrite". The article is basically in the field of biochemistry and she told ...

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by azureblue15
Fri Jun 05, 2009 5:57 am
 
Forum: Molecular Biology
Topic: What does peroxynitrite do in cytotoxicity of cells?
Replies: 0
Views: 2944
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