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Cytotoxic

Cytotoxic

(Science: pharmacology) chemicals that are directly toxic to cells, preventing their reproduction or growth. Cytotoxic agents can, as a side effect, damage healthy, noncancerous tissues or organs which have a high proportion of actively dividing cells, for example, bone marrow, hair follicles. These side effects limit the amount and frequency of drug administration.


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Vaccine for HIV

... effective. The difficulties in stimulating a reliable antibody response has led to the attempts to develop a vaccine that stimulates a response by cytotoxic T-lymphocytes. Another response to the challenge has been to create a single peptide that contains the least variable components of all the ...

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by suzidoc8
Mon Jul 23, 2012 2:47 pm
 
Forum: Microbiology
Topic: Vaccine for HIV
Replies: 1
Views: 4631

Re: Difference between T-Cell and Phagocyte?

... them in their own class II MHC molecules. This magnifies the immune response. Through their MHC II molecules, they present the antigen to either cytotoxic T cells, which can bind to and lyse infected cells, or helper T cells, which can secrete cytokines to activate B cells and cytotoxic T cells ...

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by aptitude
Sun Sep 11, 2011 7:27 am
 
Forum: Physiology
Topic: Difference between T-Cell and Phagocyte?
Replies: 10
Views: 40304

Re:

There are two things: K and NK cells, the first one is a killing cell and the second one - a natural killing cell. And cytotoxic cells are recognized as TC cells once they become activated and are generally classified as having a pre-defined cytotoxic role within the immune system. ...

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by greatmicrobiologist
Thu Aug 25, 2011 10:23 am
 
Forum: Cell Biology
Topic: Killer Cells vs. Cytotoxic Cells
Replies: 9
Views: 16616

Killer Cells vs. Cytotoxic Cells

There are two things: K and NK cells, the first one is a killing cell and the second one - a natural killing cell. And cytotoxic cells are recognized as TC cells once they become activated and are generally classified as having a pre-defined cytotoxic role within the immune system.

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by Kristine22
Mon Aug 15, 2011 6:11 am
 
Forum: Cell Biology
Topic: Killer Cells vs. Cytotoxic Cells
Replies: 9
Views: 16616

Immune System

... - Cell death can be due to phagocytosis or by the release of membrane perforating enzymes such as granzyme and perforin - both of these from NK or cytotoxic T-cells - that cause apoptosis. - Complement directly leads to the destruction of cells by causing a membrane attack complex to be formed ...

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by Babybel56
Tue May 10, 2011 7:05 pm
 
Forum: Human Biology
Topic: Immune System
Replies: 4
Views: 4119
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