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Cytokines

Cytokines

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialised glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.


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T cell differentiation

... What exactly determines the final outcome of the T cell phenotype is still unclear, but it seems it involves regulatory T cells, APC signals, cytokines and T cell receptor affinity among other things. The initial development, though, takes place in the thymus (like mentioned above), which ...

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by biohazard
Tue Apr 14, 2009 5:43 am
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 12
Views: 719

Re: T cell differentiation

Thanks for the quick reply! However there is one thing which is still confusing me, if they differentiate in the lymph then how are the cytokines which favour one differentiation or another delivered. It's just that in my notes it says NK cells and macrophages can have an effect on the type ...

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by Immunologyordie
Mon Apr 13, 2009 7:15 pm
 
Forum: Human Biology
Topic: T cell differentiation
Replies: 12
Views: 719

Chemical composition?

... water, but also any soluble components the cell has inside it, such as ions and glucose, as well as proteins it produces or takes in, including cytokines, hormones and such. Finally, since cytoplasm is everything contained within the plasma membrane, it also includes the cell organelles the ...

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by biohazard
Sun Feb 15, 2009 12:18 pm
 
Forum: Cell Biology
Topic: Chemical composition?
Replies: 2
Views: 455

?{REGENERATION}? Is it possible ???!!

... limbs. Evolutionarily, it's more important to stop a large bleed than to actually grow one back. Supposedly if we knew what cocktail of cytokines to use, we'd just pour(in a highly sophisticated manner) some on an open wound and the cells would know what to do.

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by mith
Sat Feb 14, 2009 12:08 am
 
Forum: Cell Biology
Topic: ?{REGENERATION}? Is it possible ???!!
Replies: 16
Views: 829

Enquiry about interpreting the FACS result

... that are bigger than normal cells). Alternatively you can keep your cells a few days without growth-promoting substances (if you use any, such as cytokines, interleukines etc.) and let the cells to "calm down". If you are unsure about dead cells, you may try using 7-Amino-actinomycin ...

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by biohazard
Wed Feb 04, 2009 1:00 pm
 
Forum: Cell Biology
Topic: Enquiry about interpreting the FACS result
Replies: 4
Views: 630
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