Dictionary » C » Cysteines

Cysteines

Cysteine s-conjugate n-acetyltransferase

(Science: enzyme) catalyses n-acetylation of l-cysteine thioesters to form mercapturic acids; important in drug detoxication

registry number: EC 2.3.1.80

Synonym: cscn acetyltransferase


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Re: Protein Precipitation

Things like Cu, Pb, and Hg bind strongly to the sulfurs of cysteines. They can sometimes bind to Histidines or the sidechains of Aspartates and Glutamates. They will sometimes displace structurally important metals, but the heavy metals are large (relative ...

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by blcr11
Thu Oct 16, 2008 9:58 am
 
Forum: Molecular Biology
Topic: Protein Precipitation
Replies: 3
Views: 6045

Anfinsens Experiment

Anfinsen used the protein RNase A (has a single polypeptide chain with 8 cysteines). Anfinsen wanted to know if there are substances within cells (enzymes?) that cause other proteins to fold properly into their appropriate 3D shapes. His first step was to apply ...

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by sona224
Sat Sep 29, 2007 11:02 pm
 
Forum: Genetics
Topic: Anfinsens Experiment
Replies: 5
Views: 10835

help!!!

... never thought that the ultimate sequence of the peptide dictated the choice of resin, unless it has something to do with “difficult” residues like cysteines or methionines, for example—but then, I’m not a peptide chemist, either. EMDNovabiochem (one of many potential sources) sells t-BOC and fMOC ...

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by blcr11
Mon Apr 16, 2007 3:37 pm
 
Forum: Genetics
Topic: help!!!
Replies: 2
Views: 1745

SNARE question, NO this is not my homework...

... but what I found perusing PubMed: SNAP = soluble NSF attachment protein(s?) NSF = N-ethylmaleimide sensitive factor (N-ethylmaleimide reacts with cysteines) SNARE = SNAP Receptor They seem to be involved in membrane fusion processes and so could be involved in any number of things including, but ...

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by blcr11
Wed Apr 04, 2007 8:50 pm
 
Forum: Cell Biology
Topic: SNARE question, NO this is not my homework...
Replies: 1
Views: 1142

Amino Acids

Well off the top of my head I would say that the amino acids involved would be two cysteines. I dont know of another a.a. that creates di-sulfide bonds? but I am no chemist.

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by Vagabond
Mon Feb 26, 2007 1:11 pm
 
Forum: Cell Biology
Topic: Amino Acids
Replies: 2
Views: 1548
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