Cyclic adenosine monophosphate



(1) A cyclic form of adenosine monophosphate that serves as a second messenger for signal transduction at the cellular level.

(2) A 3'-5'-cyclic ester of AMP, with a molecular formula: C10H12N5O6P


Cyclic adenosine monophosphate is produced from ATP catalyzed by adenyl cyclase located at the cell membrane. It is used for intracellular signal transduction, activation of protein kinases, and regulation of the passage of calcium ions through ion channels. It also serves as an extracellular morphogen for some slime moulds.

Related forms: 3'-5'-cyclic adenosine monophosphate.

Abbreviation: cAMP, cyclic AMP.

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