Dictionary » C » Conjugation

Conjugation

Definition

noun, plural: conjugations

(biology)

(1) The process whereby two ciliates come together in a temporary fusion to exchange micronuclear material, then separate, each being a fertilized cell.

(2) A form of sexual reproduction in certain algae and fungi where a male gamete unites with a female gamete resulting in the union of their nuclei and the subsequent formation of a zygote.

(3) The temporary joining together of two bacterial cells to transfer genetic material via the plasmid (either as solitary or as part of a chromosome) from the donor cell to the recipient cell.

(chemistry)

(1) The joining together of two compounds resulting in the formation of another compound, such as the conjugation of a toxic compound with another compound in the body to detoxify and eliminate it.

(2) A system of delocalized orbitals consisting of alternating single bonds and multiple bonds.

(general) The act or state of joining together; union; conjunction.


Supplement

Bacterial conjugation is a beneficial process in bacteria since they can acquire a gene that confers survival or a novel characteristic which enables them to thrive in harmful conditions or to utilize a new metabolite. It is through this process that resistance to antibiotics can be transferred from one bacterial cell to another.


Word origin: From Latin coniugātiō (“‘combining, connecting; conjugation’”), from coniugō (“‘join, unite together’”), from con- (“‘with’”) + iugō (“‘join, bind, connect’”).
Related forms: conjugational (adjective)

Related terms:


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Results from our forum


Review: PPMO and Vivo-Morpholinos

Conjugation of Morpholino oligos with endosomal escape moieties is bringing effective antisense techniques to rodent research. Such conjugates will likely debut soon as therapeutics. This is an open-access review of two delivery-enabled ...

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by jonmoulton
Wed Mar 25, 2009 10:58 pm
 
Forum: Genetics
Topic: Review: PPMO and Vivo-Morpholinos
Replies: 1
Views: 226

Re: Gene cloning question

... pieces of DNA molecular biologists started to notice right around the same time they began to appreciate the mechanism of bacterial conjugation. There is an OK Wiki article that gives a very very brief overview of plasmids: http://en.wikipedia.org/wiki/Plasmid Another decent source, ...

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by blcr11
Mon Dec 15, 2008 2:46 pm
 
Forum: Molecular Biology
Topic: Gene cloning question
Replies: 11
Views: 1443

Re: is it possible to knockdown a gene in a living adult now

Yes. Following are references related to conjugation of Morpholino oligos with arginine-rich peptides. Zhang B, Dong H, Stein DA, Shi PY. Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining ...

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by jonmoulton
Fri Nov 07, 2008 3:44 pm
 
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 1509

Help

... b) Transduction is useful for determing the relative order of genes on the E. coli chromosome that are separated by not more than 1 min. c) Hfr conjugation and P1 transduction can only be used when the yeast strains are haploids (i.e. not with diploids). d) None of the above D 9) Conjugation ...

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by chousta
Sat Aug 23, 2008 7:14 am
 
Forum: Genetics
Topic: Help
Replies: 1
Views: 676

Need help on a few genetics questions please.

... sister species Escherichia coli. Based upon the way Hfr's are formed, what would be a simple explanation for this difference? How can bacterial Conjugation Mapping be considered a genetic map and a physical map? From the context of microarray analysis, what is guilt-by-association, what is it ...

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by Anonymous
Sun Mar 23, 2008 11:22 pm
 
Forum: Genetics
Topic: Need help on a few genetics questions please.
Replies: 1
Views: 701
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