Dictionary » C » Conformational change

Conformational change

Conformational change

(Science: cell biology) alteration in the shape usually the tertiary structure of a protein as a result of alteration in the environment ph, temperature, ionic strength) or the binding of a ligand (to a receptor) or binding of substrate (to an enzyme).


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


question regarding the Bohr effect and Haldane effect

... to a respiratory pigmentat at a specific site...Proton binding causes a conformational change in the respiratory pigment protein that alters its oxygen affinity." ? would It ...

See entire post
by Thonzo
Tue Mar 29, 2011 1:29 pm
 
Forum: Cell Biology
Topic: question regarding the Bohr effect and Haldane effect
Replies: 0
Views: 1541

Re: Muscle Contractions

... which is anchored by troponin. Ca2+ binds to troponin causing a conformational change thus moving tropomyosin allowing the myosin binding site to become open. These binding ...

See entire post
by Jpoley
Tue Mar 01, 2011 2:42 am
 
Forum: Human Biology
Topic: Muscle Contractions
Replies: 1
Views: 5906

NA/K ATPASE

... the cell upon dephosphorylation of the active site, which will cause a conformational change and allow the na to bind to the active site.????????? c) The sodium ions will be stuck ...

See entire post
by LOLAHA
Fri Feb 19, 2010 2:27 am
 
Forum: Cell Biology
Topic: NA/K ATPASE
Replies: 4
Views: 3216

Noncompetitive inhibition and allosteric inhibition

... binders can activate as well as inhibit. Usually, there is some kind of conformational change of the protein involved. It need not alter just the conformation of the active site, ...

See entire post
by blcr11
Thu Dec 25, 2008 12:17 pm
 
Forum: Molecular Biology
Topic: Noncompetitive inhibition and allosteric inhibition
Replies: 2
Views: 28886

Noncompetitive inhibition and allosteric inhibition

... When the inhibitor binds to one active site, the enzyme undergoes a conformational change, the active site for the substrate is altered, and the enzyme cannot catalyze the reaction..." ...

See entire post
by thewax
Wed Dec 24, 2008 11:14 pm
 
Forum: Molecular Biology
Topic: Noncompetitive inhibition and allosteric inhibition
Replies: 2
Views: 28886
View all matching forum results

This page was last modified 21:16, 3 October 2005. This page has been accessed 17,827 times. 
What links here | Related changes | Permanent link