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Concanavalin A

Definition

noun

A glycoprotein lectin isolated from Canavalia ensiformis, commonly known as the jack bean.


Supplement

This lectin has been shown to stimulate T-cell production and reacts with polyglucosans causing agglutination in the blood of mammals. Is used in affinity chromatography for isolation of sugars or glycoproteins.


Abbreviation: conA

See also: lectin, mitogen.


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Mitogenesis assay?

Hi, in one of my Labs we conducted a mitogenesis assay on a splenocyte sample using Concanavalin A and Lipopolysacharride as our lectins/mitogens. Different concentrations of mitogen were added to the cell suspension and the plated suspensions were measured for absorbance ...

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by sam2400
Mon Aug 09, 2010 12:41 pm
 
Forum: Microbiology
Topic: Mitogenesis assay?
Replies: 2
Views: 3999

Re:

wait, you solved the structure of Concanavalin A? No, no :) I just went to PDB for something and found, that it's the Molecule of Month :o)) As I mentioned several times, JackBean is the name of organism from which is Concanavalin ;) http://www.biolib.cz/en/taxon/id198401/

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by JackBean
Mon Apr 12, 2010 9:36 am
 
Forum: Molecular Biology
Topic: JackBean's Concanavalin A
Replies: 3
Views: 1396

JackBean's Concanavalin A

wait, you solved the structure of Concanavalin A?

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by MrMistery
Sun Apr 11, 2010 11:11 pm
 
Forum: Molecular Biology
Topic: JackBean's Concanavalin A
Replies: 3
Views: 1396

JackBean's Concanavalin A

This month PDB's structure is the Concanavalin A from JackBean :-P For more info see http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb124_1.html There's interesting reading about permutating genes and proteins, ...

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by JackBean
Sun Apr 11, 2010 2:10 pm
 
Forum: Molecular Biology
Topic: JackBean's Concanavalin A
Replies: 3
Views: 1396


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