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Complement activation

Complement activation

The sequential activation of serum components c1 through c9, initiated by an erythrocyte-antibody complex or by microbial polysaccharides and properdin, and producing an inflammatory response.

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Immune System

... - both of these from NK or cytotoxic T-cells - that cause apoptosis. - Complement directly leads to the destruction of cells by causing a membrane ... in conjunction with MHC complexes. This allows the maturation and activation of other immune components like B-cells. - B-cells can differentiate ...

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by Babybel56
Tue May 10, 2011 7:05 pm
Forum: Human Biology
Topic: Immune System
Replies: 4
Views: 6826

More general biology questions..

... that macrophages are not? But my book suggests otherwise... 13. How are complement proteins activated? I don't really understand my book, which words ... complexes form and these activate complement proteins. The activation of one kind of complement protein results in a cascade effect ...

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by freedompeace
Fri Apr 15, 2011 12:30 pm
Forum: Cell Biology
Topic: More general biology questions..
Replies: 1
Views: 6496

Re: Cytokine - Receptor concepts

... by T lymphocites. Otherwise, T lymphocites can be usefull in B cell activation and antibody production, here it’s named T helper cell, and this ... different types of inmunoglobulins, for example: IgM ( wich acts in the complement activation), IgG and it subclasses ( acts in Fc receptor-dependent ...

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by marla
Tue Jun 01, 2010 9:08 pm
Forum: Cell Biology
Topic: Cytokine - Receptor concepts
Replies: 7
Views: 16993

Re: Morpholino review: how to knockdown

... sequence is different, the protein encoded by the fusion mRNA can complement the knocked-down protein without the Morpholino binding to the ... JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. PLoS Genet. 2007 May 25;3(5):e78. Epub ...

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by jonmoulton
Thu Jul 31, 2008 9:30 pm
Forum: Molecular Biology
Topic: Morpholino review: how to knockdown
Replies: 7
Views: 15001


... other lytic cells; or, finally, antigen-antibody complexes can activate complement, which is similar to the macrophage response in that it involves the activation and release of lytic enzymes that are intended to damage the pathogen and restrict ...

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by blcr11
Mon Jun 11, 2007 4:51 pm
Forum: Cell Biology
Topic: Antibodies
Replies: 4
Views: 4913
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