Cold agglutination

Cold agglutination

The agglutination of red blood cells by their own serum (see autoagglutination), or by any other serum when the blood is cooled below body temperature, but most pronounced below 25�C; the phenomenon results from cold agglutinins; may be seen occasionally in the blood of apparently normal persons or as a pathologic finding in patients with primary atypical pneumonia, infectious mononucleosis, and other viral diseases, certain protozoan infections, or lymphoproliferative neoplasms.

See: autoagglutination.


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