Dictionary » C » Codon




A set of three adjacent nucleotides, also called triplet, in mRNA that base-pair with the corresponding aniticodon of tRNA molecule that carries a particular amino acid, hence, specifying the type and sequence of amino acids for protein synthesis.


For example:

GCC (Guanine-Cytocine-Cytocine) → alanine GUU (Guanine-Uracil-Uracil) → valine CUA (Cytosine-Uracil-Adenine) → leucine UCA (Uracil-Cytosine-Adenine) → serine

Related terms: ambiguous codon, start codon, stop codon.

Synonym: coding triplet.
Compare: anticodon.
See also: pyrimidine, purine.

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What makes dominant allele dominant?

... Single point mutations can lead to differences in binding of miRNAs. On the protein level, there are several options, you can have premature STOP codon and the resulting peptide is too short to do its work. Or you can have change of a crucial residue to turn off your protein, like in case of Asp ...

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by JackBean
Thu Feb 27, 2014 5:20 pm
Forum: Genetics
Topic: What makes dominant allele dominant?
Replies: 7
Views: 3953

Gene cloning question

You replace one ATG with another, don't you? However if I were you, I'd be rather concerned about the start codon of the N-terminal fusion.

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by JackBean
Fri Feb 07, 2014 9:38 am
Forum: Molecular Biology
Topic: Gene cloning question
Replies: 20
Views: 17647

Re: Gene cloning question

... in pET-21a, and transfer to E.coli. I clone the gene in Nde 1 site that it’s sequence is CA/TATG, My question, is The ATG of Nde1 act as a start codon in result I must delete The ATG of my sequence or I can use the ATG of vector in Nde1 site as a start codon? (NOTE: My gene is eukaryotic) Is ...

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by mohajeri
Thu Feb 06, 2014 10:01 pm
Forum: Molecular Biology
Topic: Gene cloning question
Replies: 20
Views: 17647

Re: Please help me figure this out

Look up these terms in your textbook's glossary & index: codon, frameshift. If that doesn't explain it clearly enough to make sense, try searching the terms in wikipedia. Then go back to the question again.

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by jonmoulton
Tue Oct 29, 2013 10:03 pm
Forum: Cell Biology
Topic: Please help me figure this out
Replies: 4
Views: 1212

Re: Virology - Calculations

... -1184 kb is 1184000 bases times the 660 Da per base pair gives 7.8144x10^8Daltons... Not sure where to go to further this. Somehow, I think a codon of 3 nucleotides (990 Da) factors in to this?? ahh... no! So, the size of genome is 1184 kbp (whether you express it in kbp, Mbp or bp really ...

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by JackBean
Tue Sep 17, 2013 3:58 pm
Forum: General Discussion
Topic: Virology - Calculations
Replies: 1
Views: 1615
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