(Science: chemical) An alpha-2 adrenergic agonist that crosses the blood-brain barrier. Clonidine's central actions reduce sympathetic tone. It is used as an antihypertensive agent, and has also been used in the treatment of migraine and in the diagnosis of pheochromocytoma.
chemical name: 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-
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... in these cases usually targets a decrease in sympathetic tone both centrally and peripherally. Central sympatholytics such as methyldopa or clonidine can be used. Peripheral beta-adrenergic blockade may be better tolerated by these patients than by those with neuropathic POTS. A specific ...
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