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Chromosomal

Chromosomal

Pertaining to chromosomes.


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Aneuploidy threshold

Hi! I have a question about chromosomal instability and aneuploidy which I was hoping someone could answer. I am interested in ranking ovarian cancer cell lines based on their chromosomal instability (i.e. high or low). To do this, I've ...

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by kn83
Mon Mar 16, 2015 11:38 pm
 
Forum: Cell Biology
Topic: Aneuploidy threshold
Replies: 0
Views: 67

Taqman probe design using FISH probe (need help)

... and Taqman probes have different characteristics. Probes for FISH need to be at least 1 kb long, to hybridize and "highlight" the target chromosomal DNA (metaphase chromosomes or interphase nuclei). Hydrolysis probes (such as Taqman) are very short and used in combination with other two ...

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by protoemics
Wed Feb 04, 2015 8:11 am
 
Forum: Bioinformatics
Topic: Taqman probe design using FISH probe (need help)
Replies: 2
Views: 549

Re: Chromatin

... origin and 23 of paternal origin, plus the maternally-contributed mitochondrial chromosome (which I'll ignore for the rest of this post). Counting chromosomal centromeres, there are 46 centromeres total. After replication there are still 46 centromeres, but the mass of DNA and number of chromatids ...

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by jonmoulton
Thu Sep 04, 2014 3:04 pm
 
Forum: Genetics
Topic: Chromatin
Replies: 2
Views: 4235

Meiosis prophase I crossover

Chromosomal crossover (or crossing over) is the exchange of genetic material between homologous chromosomes that results in recombinant chromosomes.” http://en.wikipedia.org/wiki/Chromosomal_crossover Question: Due to the ...

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by gs99
Fri Mar 07, 2014 9:23 pm
 
Forum: Molecular Biology
Topic: Meiosis prophase I crossover
Replies: 0
Views: 4939

Gene deletion

... (E. coli) that are drug-multiresistant and pathogenic. I would like to delete some genes in those strains using the "One step inactivation of chromosomal genes" (Datsenko and Wanner, 2000). However, I can hardly select my mutants because my transformants strains are resistants or intermediary ...

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by clefg
Wed Sep 04, 2013 3:56 am
 
Forum: Molecular Biology
Topic: Gene deletion
Replies: 5
Views: 3496
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