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Christmas disease

Christmas disease

(Science: haematology) a form of haemophilia in males that results from a deficiency of clotting factor IX, transmitted as a x-linked trait (first described in the christmas issue of British medical Journal in 1952). Inherited in similar sex-linked way to classical haemophilia.

symptoms include easy bruising, nosebleeds, bleeding gums and bleeding into muscle tissue (haematoma) or a joint space (haemarthrosis).

treatment includes the infusion of factor IX concentrates to normalize blood coagulation.

Inheritance: sex-linked (X chromosome).


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