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Chemokines

Chemokines

class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: c (chemokines, c), cc (chemokines, cc), and cxc (chemokines, cxc), according to variations in a shared cysteine motif.


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pharmaceutical biotechnology

... and recombinant versions of these products. Immunomodulators: proteins or peptides that are not antigen specific (e.g., cytokines, growth factors, chemokines, etc.) that are intended to treat disease by inhibiting or modifying a pre-exisiting immune response; and proteins or peptides intended to ...

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by kcnq1ot1
Tue Nov 27, 2007 2:47 pm
 
Forum: Molecular Biology
Topic: pharmaceutical biotechnology
Replies: 6
Views: 813

The Fiber Disease

... 5 (CCR5) in the nerves that respond to environmental cues. Somatostatin is a hormone that mediates a wide range of activities in humans and chemokines play an important role in the immune system. The CCR5 receptor used is also the gateway that HIV/AIDS virus uses to enter cells. Both receptors ...

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by J Jill
Sun Sep 17, 2006 1:20 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 748693

Cure for AIDS

... p51 and p66, integrase p32, and protease p11. In addition to the CD4 receptor, a coreceptor known as a chemokine is needed for HIV infection. Chemokines are cell surface fusion-mediating molecules. Such coreceptors include CXCR4 and CCR5. Their presence on cells can aid binding of the HIV ...

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by victor
Thu Jan 19, 2006 2:11 pm
 
Forum: Microbiology
Topic: Cure for AIDS
Replies: 49
Views: 7626


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