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Dictionary » C » Case-control study Case-control studyDefinition noun An epidemiological study used to identify factors that may contribute to a medical condition by comparing patients who have the disease or condition of interest (the cases) with those who do not have the disease or condition of interest (the controls).
This study starts by identifying the individuals with the disease or condition of interest and their history of exposure to identified or suspected factors. Their past exposures to risk factors are then compared to the history of similar exposures of other individuals who resemble the cases but do not have the disease or condition of interest.
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