Carrier-free

... and the origin are overlaping in some places, and doing "partial introduction" of new genetic material to the existing body of the carrier. Are needed tests, direct experiments, but I do not have access to modern laboratory (physical, chemical and biological). Therefore, I am forced ...

See entire post

1. Cannot be x-linked recessive: in order to have an affected female progeny, you need to have heterozygous carrier mother AND father. That means that father would be affected too (single X chromosome). 2. Thus, it's an autosomal (see above) recessive (since neither parent affected, ...

See entire post

... than females are affected. 2. Affected sons are usually born to unaffected mothers; thus, the trait skips generations. 3. Approximately half of a carrier (heterozygous) mother’s sons are affected. 4. Never passed from father to son. 5. All daughters of affected fathers are carriers. Also I am ...

See entire post

... differ slightly, this can give rise to the two traces in the sequence (it's a single-nucleotide polymorphism). This suggests the female may be a carrier with a DMD allele and a wild-type allele for dystrophin, but the pedigree makes it look like she is expressing the DMD phenotype. That confuses ...

See entire post

... differ slightly, this can give rise to the two traces in the sequence (it's a single-nucleotide polymorphism). This suggests the female may be a carrier with a DMD allele and a wild-type allele for dystrophin, but the pedigree makes it look like she is expressing the DMD phenotype. That confuses ...

See entire post