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Carcinoma

Carcinoma

(Science: oncology) a malignant new growth that arises from epithelium, found in skin or, more commonly, the lining of body organs, for example: breast, prostate, lung, stomach or bowel. Carcinomas tend to infiltrate into adjacent tissue and spread (metastasize) to distant organs, for example: to bone, liver, lung or the brain.

Origin: gr. Karkinoma from karkinos = crab, cancer


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How to go about creating a stably-transfected cell line

Hi everyone, I am a PhD student and I'm new to these boards. I'm using P19 mouse embryonal carcinoma cells in my research, and I differentiate them into neurons using retinoic acid. I wish to create a stable clone expressing a GFP-fusion neurotransmitter receptor, of ...

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by JustinNg
Mon Sep 17, 2012 9:26 am
 
Forum: Molecular Biology
Topic: How to go about creating a stably-transfected cell line
Replies: 1
Views: 1756

cancer spread biology?

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by suzidoc8
Mon Jul 23, 2012 3:10 pm
 
Forum: General Discussion
Topic: cancer spread biology?
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Views: 10316

LOH/somatic inactivation/biallelic inactivation?

... inactivation not always lead to loss of heterozygosity? e.g. "The tumour suppressor gene p53 is frequently inactivated in gastric carcinoma by loss of heterozygosity (LOH), missense mutations and frame shift deletions" (http://www.biology-online.org/articles/cellular_molecular_aspects_gastric/molecular_mechanisms_gastric_carcinogenesis.html) ...

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by Mike72
Thu Mar 01, 2012 4:04 pm
 
Forum: Genetics
Topic: LOH/somatic inactivation/biallelic inactivation?
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Molecular Cell Biology

... and by fluid phase endocytosis (FPE). The efficiencies of these 2 pathways were compared experimentally by incubation of the human A431 epithelial carcinoma cell line with epidermal growth factor (EGF) to measure RME, and horseradish peroxidase (HRP) to measure FPE. A quantitative analysis was ...

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by Freckles
Wed Dec 07, 2011 11:24 pm
 
Forum: Cell Biology
Topic: Molecular Cell Biology
Replies: 5
Views: 4089

Sarcoma vs Carcinoma

I have same basic questions. I have a problem defining what carcinoma means: a tumour originating in the epithelium, or can it also come from endothelium, or basically any tissue that derives from the embryonic ectoderm? Same with sarcoma: any type of ...

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by kk
Mon Nov 28, 2011 4:50 pm
 
Forum: Human Biology
Topic: Sarcoma vs Carcinoma
Replies: 0
Views: 1507
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