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Capsid

Capsid

a protein coat that covers the nucleoprotein core or nucleic acid of a virion. Commonly shows icosahedral symmetry and may itself be enclosed in an envelope (as in the Togaviridae). The capsid is built up of subunits (some integer multiple of 60, the number required to give strict icosahedral symmetry) that self assemble in a pattern typical of a particular virus. The subunits are often packed, in smaller capsids, into 5 or 6 membered rings (pentamers or hexamers) that constitute the morphological unit (capsomere). The packing of subunits is not perfectly symmetrical in most cases and some units may have strained interactions and are said to have quasi equivalence of bonding to adjacent units. A variety of leaf bug.The outer covering of protein surrounding the nucleic acid of a virus.The protein coat that surrounds the dna or mrna of a virus.


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Re:

Yes capsid proteins can self asemble in solution. I am not sure what you mean by manufactured, but the genes can be cloned in plasmids, and protein can be synthesized without anything else from plamids. Re self assembly: do ...

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by raneynickel
Sun Aug 09, 2009 12:40 pm
 
Forum: Microbiology
Topic: some general capsid questions
Replies: 3
Views: 94

some general capsid questions

Yes capsid proteins can self asemble in solution. I am not sure what you mean by manufactured, but the genes can be cloned in plasmids, and protein can be synthesized without anything else from plamids.

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by canalon
Sat Aug 08, 2009 1:47 am
 
Forum: Microbiology
Topic: some general capsid questions
Replies: 3
Views: 94

some general capsid questions

What kind of proteins are the capsid shells made of? Will a collection of capsid proteins in soln' generally form an icosahedral (or other geometric shape, depending on protein..) shape; Will they from encapsulating shapes on their own? ...

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by raneynickel
Sat Aug 08, 2009 12:50 am
 
Forum: Microbiology
Topic: some general capsid questions
Replies: 3
Views: 94

Re: Viral Enzymes

... for RNA viruses). These are then packed into the viral particle during the viral assembly. So, because they already carry the enzyme within the capsid, it is ready to use when the virus offloads its "cargo" into their target cell. In the cell, all parts of the virus are then produced ...

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by biohazard
Wed May 27, 2009 6:46 am
 
Forum: Microbiology
Topic: Viral Enzymes
Replies: 1
Views: 472

Viral Enzymes

... so I am re-posting this here ) For the viruses that must carry a specific enzyme (eg. viruses with ssDNA, -ssRNA genomes): 1. It is carried in the capsid AND coded for in their genomes, right? 2. since they need this enzyme before they can use their genome, how do they ensure that a lot is transcribed? ...

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by SysBio
Tue May 26, 2009 7:36 am
 
Forum: Microbiology
Topic: Viral Enzymes
Replies: 1
Views: 472
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