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Cap binding protein

Cap binding protein

(Science: molecular biology, protein) protein (24 kD) with affinity for cap structure at 5' end of mrna that probably assists, together with other initiation factors, in binding the mrna to the 40S ribosomal subunit. Translation of mrna in vitro is faster if it has a cap binding protein.


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Re: translation from DNA

That's a reasonable idea. I can imagine a ribosome directly binding to DNA to translate the DNA codons directly into protein. We can't really tell why that didn't happen, as much of the early development of life ...

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by jonmoulton
Mon Sep 29, 2014 3:03 pm
 
Forum: Molecular Biology
Topic: translation from DNA
Replies: 2
Views: 315

Re: Any ideas for vaccine development or anti-viral drugs???

... DL, Nelle T, Iversen PL, Bavari S, Aman MJ. Involvement of Vacuolar Protein Sorting Pathway in Ebola Virus Release Independent of TSG101 Interaction. ... The discovery process involved identification of optimal transcript binding sites for PMO based RNA-therapeutics followed by screening for effective ...

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by jonmoulton
Mon Sep 15, 2014 3:04 pm
 
Forum: Cell Biology
Topic: Any ideas for vaccine development or anti-viral drugs???
Replies: 2
Views: 535

What makes dominant allele dominant?

... about expression. The difference can be anywhere from transcription to protein post-translational modifications. There can be mutation in the promotor changing significantly expression. If the binding of ribosome will be impaired, there will be much less of protein made. Single ...

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by JackBean
Thu Feb 27, 2014 5:20 pm
 
Forum: Genetics
Topic: What makes dominant allele dominant?
Replies: 7
Views: 4428

cAMP 2nd Messenger Pathway and Experiments

... 1: Cell membranes from cyc- cells were isolated and mixed with protein extracts from cells which exhibited adenylyl cyclase activity (cyc+ ... It interacts with GTP regulatory site to prohibit the GDP from binding. If ATP or GTP were eliminated from the reaction, it would not be ...

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by mkay28
Tue Sep 24, 2013 10:43 pm
 
Forum: Cell Biology
Topic: cAMP 2nd Messenger Pathway and Experiments
Replies: 2
Views: 2260

The question about TATA sequence flexibility

... I read this article about TATA-Binding Protein: Second, the protein uses specially-placed amino acids to interact with DNA bases. ...

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by Fantomas
Sat Aug 31, 2013 10:57 am
 
Forum: Molecular Biology
Topic: The question about TATA sequence flexibility
Replies: 1
Views: 1798
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