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C5a peptidase

C5a peptidase

(Science: enzyme) streptococcus pyogenes enzyme inactivates complement 5a by cleaving at lysine 68, removing a six-amino acid fragment

Pharmacological action: complement inactivators

registry number: EC 3.4.99.-

Synonym: streptococcus c5a peptidase, gbs c5a-ase, group b streptococci c5a-ase, scpa protein


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peptidases

if anybody can please help me with this it would be really appreciated: how do cells prevent their own peptidases from digesting their own proteins and killing themselves? i think it has something to do with peptidase inhibitors but not exactly sure if its right.... could ...

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by iloza1128
Thu Sep 27, 2007 9:59 pm
 
Forum: Molecular Biology
Topic: peptidases
Replies: 1
Views: 384

The Fiber Disease

... of fusion constructs defined three types of export sequence: (1) non-cleavable, membrane-spanning sequences, (2) signal peptides with signal peptidase (SPase) I-like cleavage sites, and (3) signal peptides with SPase II-like lipoprotein-cleavage sites which, like most other mycoplasmal lipoprotein ...

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by Nadas Moksha
Tue Nov 14, 2006 5:17 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 748648

enzyme question

peroxidase is an enzyme that breaks down toxis hydrogen peroxide in your liver into water and oxygen. IN the liver, pH is of normal cell pH. Peptidase on the other hand catalyses the breakdown of protein into amino acids inside the stomach. The stomach walls release acid which provides an optimal ...

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by keef
Sun Nov 12, 2006 5:19 am
 
Forum: Cell Biology
Topic: enzyme question
Replies: 3
Views: 1257

bacterial cell walls and digestion by proteases

... organisms use a protease which recognizes “usual” L-amino acids. 2. The oligopeptide bridges of peptidoglycan contain only D-amino acids. Then L-peptidase cannot digest D-amino acid bridge. Let’s look at Bacteria cell wall. Chemical structure of peptidoglycan: http://www.biology-online.org/biology-forum/userfiles/pg_154.jpg ...

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by druid
Mon Nov 06, 2006 10:04 pm
 
Forum: Microbiology
Topic: bacterial cell walls and digestion by proteases
Replies: 1
Views: 830

The Fiber Disease

brick by brick demolition style.... "each artificial peptidase is engineered so that the class of residue it is designed to attack is not exposed on its own external physical surface [112] -- that is, each artificial enzyme minimally exhibits strong ...

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by Nadas Moksha
Mon Oct 02, 2006 4:33 am
 
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 748648
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