• Home
  • Forum
  • Dictionary
  • Articles
  • Tutorials
  • Books
  • Directory
  • Share your work


Dictionary » B » Bromouracil

Bromouracil

Bromouracil

(Science: chemical) 5-bromo-2,4(1h,3h)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in dna. It is used mainly as an experimental mutagen, but its deoxyriboside (bromodeoxyuridine) is used to treat neoplasms.

Pharmacological action: antimetabolites, mutagens.

chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-bromo-


Please contribute to this project, if you have more information about this term feel free to edit this page



Results from our forum


Re: about chargaff's rule

... but on the other strand, because a C was bound, the A is replaced by a G. This is complex chemistry though. The same can happen when the mutagen 5-bromouracil is precent. Normally U will bind A, but 5-bromouracil i=can tautomerize to a so-called enol form which has a higher frequence. It binds ...

See entire post
by sdekivit
Tue Aug 15, 2006 3:19 pm
 
Forum: Molecular Biology
Topic: Chargaff's bases
Replies: 15
Views: 5573


This page was last modified 21:16, 3 October 2005. This page has been accessed 1,052 times. 
What links here | Related changes | Permanent link