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Bradykinin

Bradykinin

(Science: protein) vasoactive nonapeptide (RPPGFSPFR) formed by action of proteases on kininogens. Very similar to kallidin (which has the same sequence but with an additional N terminal lysine). Bradykinin is a very potent vasodilator and increases permeability of post capillary venules, it acts on endothelial cells to activate phospholipase A2. It is also spasmogenic for some smooth muscle and will cause pain.


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Contact Dermatitis ( allergic)

... nickel but can be rubber and all sorts of things). The complex attaches to a mast cell IgE receptor which releases mediators such as histamin and bradykinin upon binding IgE loaded with antigen to its IgE receptor. This releases causes the itching etc and that's what's meant be an 'overreaction'. ...

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by weesper
Tue Aug 15, 2006 9:52 am
 
Forum: Human Biology
Topic: Contact Dermatitis ( allergic)
Replies: 3
Views: 868

G-proteins

... PIP2) generating the second messengers, diacylglycerol (DAG) and inositoltrisphosphate (IP3). This class of receptors includes the angiotensin, bradykinin and vasopressin receptors. 3. A novel class of GPCRs are the photoreceptors. This class is coupled to a G-protein termed transducin that ...

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by blindcat35
Sat Feb 04, 2006 6:31 am
 
Forum: Cell Biology
Topic: G-proteins
Replies: 4
Views: 3672


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