Dictionary » B » Blockade



1. Intravenous injection of large amounts of colloidal dyes or other substances whereby the reaction of the reticuloendothelial cells to other influences (e.g., by phagocytosis) is temporarily prevented.

2. Arrest of peripheral nerve conduction or transmission at autonomic synaptic junctions, autonomic receptor sites, or myoneural junctions by a drug.

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Hyperadrenergic POTS

... sympathetic tone both centrally and peripherally. Central sympatholytics such as methyldopa or clonidine can be used. Peripheral beta-adrenergic blockade may be better tolerated by these patients than by those with neuropathic POTS. A specific genetic abnormality has been identified in a kindred ...

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by rmorrison
Wed Mar 19, 2014 5:38 pm
Forum: Human Biology
Topic: Hyperadrenergic POTS
Replies: 0
Views: 6049

how do drugs affect cellular processes?

... effect in general? I think the best answer to that question is that most drugs block or otherwise inhibit. But its true every drug effects the blockade in a different way. That raises an interesting question. Are there drugs out there that cause upregulation of cell processes already happening ...

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by daniel.kurz
Mon Oct 24, 2011 3:27 am
Forum: Cell Biology
Topic: how do drugs affect cellular processes?
Replies: 6
Views: 3379

Antimuscarinic drugs

... (the last part was a joke, kind of.) "High therapeutic doses of atropine cause tachycardia in innervated and spontaneously beating hearts by blockade of vagal slowing" Q2. Does this mean it can increase the rate only, but not restart a stopped heart?

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by raneynickel
Thu Sep 24, 2009 6:50 am
Forum: Physiology
Topic: Antimuscarinic drugs
Replies: 3
Views: 5708

Re: is it possible to knockdown a gene in a living adult now

... Oligomers in Cell Cultures and in Mice. Mol Ther. 2008 Apr 29; [Epub ahead of print] Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Mol Cancer Ther. 2008 Mar;7(3):712-20. Stone JK, Rijnbrand R, ...

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by jonmoulton
Fri Nov 07, 2008 3:44 pm
Forum: Genetics
Topic: is it possible to knockdown a gene in a living adult now
Replies: 10
Views: 17137


... functions. Because these conditions, especially female cancers, are associated with estrogen, a number of anticancer treatments involve estrogen blockade: drugs that prevent estrogen from binding to its receptors. As a result, the receptors remain in an inactive form.

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by chenhongxia
Fri Aug 15, 2008 1:47 am
Forum: Physiology
Topic: Estrogen
Replies: 4
Views: 12573
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